Chronic Melatonin Use Linked to Increased Heart Failure Risk
Researchers have found that taking melatonin for a year or longer may raise the risk of heart failure. Although melatonin is a popular sleep aid, its long-term effects remain uncertain as usage becomes more widespread.
Study Findings on Melatonin and Heart Health
A recent preliminary study examined medical records of individuals with chronic insomnia. It showed that those prescribed melatonin for at least one year had a higher likelihood of developing heart failure and a greater risk of death from any cause.
“These findings challenge the perception of melatonin as a benign chronic therapy and underscore the need for randomized trials to clarify its cardiovascular safety profile,” the researchers noted.
Melatonin: Natural Hormone and Supplement
Melatonin is a hormone our bodies naturally produce, mainly regulating the sleep-wake cycle. Synthetic melatonin is approved in some countries, such as the U.K., for treating insomnia in people over 55. In the U.S., melatonin is widely available over-the-counter as a supplement.
Safety Considerations
Using melatonin for short periods, like for jet lag, appears generally safe for adults, though it may not be appropriate for children.
Study Limitations and Future Research
The authors caution that the study has important limitations but believe the findings justify further research into the potential cardiovascular risks of long-term melatonin use.
Author’s Summary
Long-term melatonin use may pose heart risks, emphasizing the urgent need for clinical trials to fully assess its cardiovascular safety.