Heart Health: Long-Term Melatonin Use Linked to Cardiovascular Risk
New research indicates that individuals with insomnia who take melatonin supplements for over a year may face an increased risk of heart failure compared to non-users. The study found that long-term melatonin users were more likely to receive a heart failure diagnosis, require hospitalization for this condition, or experience death from any cause.
This research will be presented at the American Heart Association’s Scientific Sessions 2025 in New Orleans. As the study is preliminary and has not yet undergone peer review, it does not prove a direct cause-and-effect between melatonin use and heart failure risk.
“Melatonin supplements may not be as harmless as commonly assumed.”
The researchers highlighted safety concerns regarding prolonged melatonin use and stressed the need for further studies to evaluate cardiovascular safety. They also pointed out that many melatonin products are available over the counter without prescriptions, lack regulation, and are often used without medical supervision.
Key Points
- Long-term melatonin use (over one year) is linked to higher heart failure risk.
- The study shows correlation, not causation, and requires further validation.
- Melatonin supplements are widely accessible without healthcare guidance.
- Ongoing research is essential to ensure the cardiovascular safety of these supplements.
Summary: Prolonged melatonin use for insomnia may raise heart failure risk, highlighting the importance of caution and further cardiovascular safety research.